This refers to the stage of mixing of dosh with the those factors which helps to generate a disease called dosh dushya sammurchhana. The sign & symptoms developed on the body according to the involvement of dosha (vata, pitta, and kapha) and dushya (rasha, rakta, mans, meda, asthi, majja, shukra)
if dosh dushya sammurchhana takes place between pitta (dosh) and rakta (dushya) then the sign & symptoms developed over the body are small furuncles over the skin which have burning sensation. The sign & symptoms developed at this stage is called purvaroopa of the disease.
• Differentiated symptoms first begin to appear from the location.
• Manifested symptoms being used by modem medicine for classification & diagnosis of disease