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The evolution of disease: Shat-Kriyakal (Pathogenesis)

Ayurveda describes the evolution of disease in six stages which describe the whole processes or activities that happen in the body from exposure to the disease causing factors to disease manifestation. The disease causing factors when exposed to the body cause the disturbance of equilibrium of three doshes. The disequilibrium of doshes leads to the increment or decrement of their volume. The increment or decrement of particular Dosha causes the disease. Before manifestation of disease, Ayurveda describes the seven minute stages. First the Dosha get accumulated and then vitiated. The vitiated Dosha starts to spread throughout the body. When it is stopped or it reaches in appropriate place it gets localized. It starts to act. So the primordial signs and symptoms or clinical manifestations of diseases occur. Ayurveda describes signs and symptoms as the result of complication of disease. So it prescribes to treat the disease before its manifestations or complication. The six stages are:

1.Sanchaya (Accumulation of Dosha)
2.Prakopa (Vitiation of Dosha)
3.Prasara (Spreading of Dosha)
4.Sthansamshraya ( Localization of Dosha)
5.Vyakta (stage of clinical manifestation)
6.Bheda ( stage of complications of the diseases)

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